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List of neuroscience databases
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A number of online neuroscience databases are available which provide information regarding gene expression, neurons, macroscopic brain structure, and neurological or psychiatric disorders. Some databases contain descriptive and numerical data, some to brain function, others offer access to 'raw' imaging data, such as postmortem brain sections or 3D MRI and fMRI images. Some focus on the human brain, others on non-human.

As the number of databases that seek to disseminate information about the structure, development and function of the brain has grown, so has the need to collate these resources themselves. As a result, there now exist databases of neuroscience databases, some of which reach over 3000 entries.

Neuroscience databases

NameDescriptionOrganismLevel (gene, neuron, macroscopic)Data (MRI, fMRI, images, descriptive, numerical)DisorderRegister to view data?Ref.
A Virtual Library for Behavioral Performance in Standard Conditions – Rodent Spontaneous Activity in an Open Field during Repeated Testing and after Treatment with Drugs or Brain LesionsResearch using an animal model of obsessive-compulsive disorder employed a standardized paradigm where the behavior of rats in a large open field was video recorded for 55 min on each test.RatMacroscopicVideoObsessive-compulsive disorderNo2
Allen Brain AtlasAtlas, stained sections from brains showing development and gene expressionMouse, HumanMacroscopic, GeneImagesHealthyNo3
Alzheimer's Disease Neuroimaging Initiative (ADNI)Structural MRI imagesHumanMacroscopicMRI datasetsHealthy and Alzheimer's diseaseYes4
Big Brain3D reconstruction of complete brain from cell-body stained histology sections at 20 micron isotropic resolutionHumanMicroscopicImagesHealthyNo5
BIRN fMRI and MRI datafMRI, MRI scans and atlases for human and mouse brainsMouse, HumanMultilevel: brain regions, connections, neurons, gene expression patternsMRI datasets, fMRI datasetsHealthy, ElderlyNo
Bipolar Disorder Neuroimaging DatabaseMeta-analysis and database of MRI studiesHumanMacroscopicDescriptive, numericalBipolar DisorderNo6
Brain Architecture Management SystemOnline resource for information about neural circuitryRat, mouse, humanMultilevel: brain regions, connections, neurons, gene expression patternsDescriptive, numericalHealthyNo
Brain CloudGene expression in the human prefrontal cortexHumanGene expression patternsDescriptive, numericalHealthyNo
Brain-CODEA multi-modal, cross-disorder platform for integrated neuroscience research and data by the Ontario Brain Institute.Human, AnimalMultimodal datasets (clinical, imaging, molecular, etc.)Descriptive, numerical, imaging, molecular, geneticsNeurodevelopmental, Cerebral Palsy, Epilepsy, Depression, Neurodegeneration, ConcussionYes7
Brain-Development.orgStructural MRI images and AtlasesHumanMacroscopicMRI datasetsFetuses, healthy and prematurely born neonatesYes8
Braingraph.orgBraingraphs computed from the Human Connectome Project dataHumanMacroscopic, up to 1015 nodesdirected and undirected graphs in anatomically annotated GraphML formatHealthyNo9
BraininfoAtlas, schematic atlas of Macaca fascicularisMacaqueMacroscopicSchematic imagesHealthyYes
Brain Machine Interface PlatformDifferent types of data related to brain machine interfaceHuman, MonkeyMacroscopic, NeuronImages, NumericalHealthyNo
BrainMap.orgfMRI coordinate databaseHumanMacroscopicDescriptiveHealthyYes10
BrainMapsAtlas, high resolution stained sections from brainsHuman, primate and non-primate (14 species in all)Neuron and MacroscopicImagesHealthyNo11
Brain/MINDS DataportalAtlas, in-vivo and ex-vivo MRI scans, ECoG recordingsCommon Marmoset, HumanMacroscopicImagesHealthyNo12
Brede DatabasefMRI and PET coordinate databaseHumanMacroscopicDescriptiveHealthyNo13
Brainmuseum.org / MSU Brain Biodiversity BankAtlas, stained sections from brains and MRI imagesHuman and 62 other speciesMacroscopicImagesHealthyNo
Brainomics/LocalizerfMRI and MRI scans, behavioral dataHumanMacroscopicImages, NumericalHealthyNo14
BuzLabDB: The Buzsaki Lab DatabankElectrophysiological recordings performed in freely moving rats and mice collected by investigators in the Buzsaki LabMice and ratsMultiscaleSpike trains, LFP, Raw ephys dataHealthyNo1516
Caltech Subcortical AtlasMRI scansHumanMacroscopicMRIHealthyNo17
Cambridge Centre for Ageing and Neuroscience (Cam-CAN)MRI, fMRI, MEG data for ~700 population-derived healthy adults aged 18–88HumanMacroscopicImages, Descriptive, NumericalHealthyNo18
The Cancer Imaging ArchiveMRI, CT, and PET imaging of cancer patients with supporting clinical data (in many cases)HumanMacroscopicImages, Descriptive, NumericalCancerNo19
Cerebellar Development Transcriptome DatabaseAtlas, stained sections from mouse brains showing cerebellar development and gene expressionMouseMacroscopic, GeneImagesHealthyNo20
Collaborative Research in Computational Neuroscience (CRCNS.org)Many kinds of neuroscience results that are relevant for modelingHuman and several other speciesMultiscaleSpike trains, LFP, MUA, MRIHealthyYes
DANDI: Distributed Archives for Neurophysiology Data Integrationcellular neurophysiology data including electrophysiology, optophysiology, and behavioral time-series, and images from immunostaining experimentsHuman and several other speciesMultiscaleSpike trains, LFP, MUA, MRIHealthy
Database for Reaching Experiments And Models (DREAM)Reaching data (behavioral, generalization, adaptation, learning, spike, fMRI, uncertainty)Human and monkeyMacroscopicKinematic, Spike, fMRIHealthyYes
The fMRI Data CenterfMRI datasets from published studiesHumanMacroscopicfMRI datasetsHealthyYes21
GLIMPS Project (GLucose IMaging in Parkinsonian Syndromes)International FDG-PET scan neurodegenerative disease databaseHumanMacroscopicFDG-PET imagesParkinson's disease (PD), Alzheimer's disease (AD), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), etc.Yes
Hippocampome PortalCircuitry, neural types, electrophysiologyAdult humanNeuronCell morphology, electrophysiology, region makeup, connectivityHealthyYes2223
IBA: Infant Brain AtlasInfant brain atlases from 2 weeks to 2 years of ageHuman infantsMacroscopic, microscopic, brain regionsMRIHealthyNo24
International Epilepsy Electrophysiology Database (IEEG.org)EEG, metadata, imaging, annotations on dataHumans and animal models of epilepsyEEG, local fields, micro-ECoGElectrophysiologyNon-healthy, several healthyYes
International Neuroimaging Data-sharing Initiative (INDI)Functional connectivity data from many different groupsInvertebrates (47 species in all)MacroscopicFunctional connectivityHealthy, non-healthyYes
Invertebrate Brain PlatformPhotos of dissections of invertebrates nervous systemsInvertebrates (47 species in all)MacroscopicPhotosHealthyNo
In vivo human phantomUltrahigh resolution MRI data of a single participant including 150 μm ToF angiography, 250 μm T1-weighted MPRAGE, 330 μm QSM, 450 μm T2-weighted TSE, 800 μm DTI, one hour continuous 1.8 mm rs-fMRI and structural data acquired over more than a decadeHumanMesoscopicStructural MRI with various contrasts, microstructure MRI and functional MRIHealthyNo25
JuBrain atlasProbabilistic cytoarchitectonic 3D maps of the human brainHumanMesoscopicStructuralHealthyNo2627
Kymata AtlasFunctional atlas of the human cortexHumanMacroscopicFunctionalHealthyNo28
Major Depressive Disorder Neuroimaging DatabaseMeta-analysis and database of MRI studiesHumanMacroscopicDescriptive, numericalMajor Depressive DisorderNo29
Marmoset Gene AtlasGene expression in the common marmoset whole brainCommon MarmosetMacroscopic, GeneImagesHealthyNo30
Mouse Brain LibraryAtlas, stained sections from mouse brainsMouseMacroscopicImagesHealthyNo31
MouseLightComplete, whole-brain reconstructionsMouseNeuronCell morphology, projectome connectivityHealthyNo32
NeuroDataVolumetric datasets, atlases, and connectomics researchMultipleMultiscaleImages (3D, 4D)VariousNo
Neuroelectro.orgElectrophysiology of neuronsHuman, othersNeuronElectrophysiological properties and dataHealthyNo33
Neuromorpho.org3D models of real neuronsHuman, rat, mouse, monkey, othersNeuronImages and 3D dataHealthyNo34
Neuromorphometrics.comManually labeled MRI Brain ScansHumanMacroscopicT1-weighted MRI, labeled volumesHealthyNo
NeuronDBDatabase of Neuron properties and classificationHumanNeuronDescriptiveHealthyNo35
Neuroimaging Tools and Resources Collaboratory (NITRC)Award-winning free collaboratory with over 1000 neuroinformatics software tools, imaging datasets, and community resources including forums and events.Human, mouse, rat, otherMicroscopic, macroscopicDatasetsHealthy and diseasedNo
Open Access Series of Imaging Studies (OASIS)Structural MRI imagesHumanMacroscopicMRI datasetsHealthy and Alzheimer's diseaseYes36
Open Connectome ProjectDatabase of different circuitry frameworks and neuroimaging datasets, including volumetric datasets, atlases, and connectomics researchHuman, mouse, bat, zebrafish, insect, otherMultilevel: brain regions, connections, neurons, gene expression patternsImages and 3D dataHealthyNo37
openfnirsa meta-database specific to fNIRS data. The “Openfnirs meta-database” (https://openfnirs.org/data/) is a part of the openfnirs initiative whose mission is to foster the development of an fNIRS ecosystem and to promote the open dissemination of fNIRS hardware and software, as well as provide access to resources, documentation and training opportunities for fNIRS users.HumanMacroscopicfNIRS (Functional_near-infrared_spectroscopy)Healthy and eventually various diseasesNo38
OpenNeuroLarge and diverse collection of raw data from various research studies distributed under permissive licenses (CC0 and CC BY). All datasets are formatted according to the same format (Brain Imaging Data Structure) and can be accessed via Amazon S3.HumanMacroscopicFunctional, structural, diffusion MRI, and Magnetoencephalography datasetsHealthy and various diseasesNo39
Open MEG Archive (OMEGA)Magnetoencephalography, structural MRI datasets, and demographicsHumanMacroscopicMEG, T1 MRI datasets, demographic dataHealthy, ADHD, Traumatic brain injuryYes40
The PAIN RepositoryStructural, Diffusion and Functional MRI datasetsHumanHuman MacroscopicMRI datasets and MetadataHealthy and Pain ConditionsYes41
Pig Brain AtlasPig Brain Atlas is a three-dimensional MRI-based averaged brain and atlas of the neonatal piglet (Sus scrofa).Pig (Sus scrofa)MacroscopicStructural MRIHealthyYes42
Primate Cell Type DatabasePrimateDatabase.com, a publicly available web-accessible archive of intracellular patch clamp recordings and highly detailed three-dimensional digital reconstructions of neuronal morphology.Non-human primate and humanNeuronElectrophysiology, Morphology and 3-d ReconstructionsHealthyNo
SchizConnectSchizConnect is an open, public search-and-download virtual database for schizophrenia neuroimaging (MRI) images and related data.HumanMacroscopicStructural, Diffusion and Functional MRI datasets, cognitive and clinical assessmentsSchizophrenia (+ siblings), Bipolar Disorder, Controls (+ siblings)Yes43
Temple EEG DatabaseOver 30,000 clinical EEGs and accompanying neurologist reportsHumanMacroscopicEEGHealthy and various diseasesYes44
Ultrahigh resolution T1-weighted whole brain MR datasetT1-weighted MR data acquired using prospective motion correction at an ultrahigh isotropic resolution of 250 μm.HumanMesoscopicStructural MRI dataset including scanner's raw to processed dataHealthyNo45
UNC-Wisconsin Neurodevelopment Rhesus MRI DatabaseStructural and Diffusion Weighted MRI images in Native and Atlas SpaceMacaqueMacroscopicMRI datasetsHealthyNo
Whole Brain AtlasAtlas, Structural MRI images and PET imagesHumanMacroscopicImagesHealthy and various diseasesNo
NeuroVaultUnthresholded statistical maps from MRI and PET studies.HumanMacroscopicImagesHealthy and various diseasesNo46

Databases of neuroscience databases

NameDescriptionOrganismLevel (gene, neuron, macroscopic)Data (MRI, fMRI, images, descriptive, numerical)DisorderRegister to view data?Ref.
Neuroscience Information FrameworkA meta database of neuroscience-relevant data incorporating over 100 databases.Human, mouse, rat, wormMicroscopic, macroscopicDatasetsHealthy and diseasedNo47

See also

References

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