Phosphoinositide 3-kinase regulatory subunit 5 is an enzyme that in humans is encoded by the PIK3R5 gene.
Interactions
PIK3R5 has been shown to interact with PIK3CG.3
Further reading
- Johnson C, Marriott SJ, Levy LS (2007). "Overexpression of p101 activates PI3Kgamma signaling in T cells and contributes to cell survival". Oncogene. 26 (49): 7049–57. doi:10.1038/sj.onc.1210504. PMID 17486067.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Suire S, Coadwell J, Ferguson GJ, et al. (2005). "p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma". Curr. Biol. 15 (6): 566–70. Bibcode:2005CBio...15..566S. doi:10.1016/j.cub.2005.02.020. PMID 15797027. S2CID 12255918.
- Voigt P, Brock C, Nürnberg B, et al. (2005). "Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma". J. Biol. Chem. 280 (6): 5121–7. doi:10.1074/jbc.M413104200. PMID 15611065.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Metjian A, Roll RL, Ma AD, et al. (1999). "Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus". J. Biol. Chem. 274 (39): 27943–7. doi:10.1074/jbc.274.39.27943. PMID 10488142.
- Krugmann S, Hawkins PT, Pryer N, et al. (1999). "Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits". J. Biol. Chem. 274 (24): 17152–8. doi:10.1074/jbc.274.24.17152. PMID 10358071.
References
Brock C, Schaefer M, Reusch HP, et al. (Jan 2003). "Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma". J Cell Biol. 160 (1): 89–99. doi:10.1083/jcb.200210115. PMC 2172741. PMID 12507995. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172741 ↩
"Entrez Gene: PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5, p101". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23533 ↩
Brock C, Schaefer M, Reusch HP, et al. (Jan 2003). "Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma". J Cell Biol. 160 (1): 89–99. doi:10.1083/jcb.200210115. PMC 2172741. PMID 12507995. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172741 ↩