Pinc

<p>Pinc (pregnancy induced noncoding RNA) is a <a href="/facts/Long_non-coding_RNA/FHyAb6hP">long non-coding RNA</a>. It was originally identified in the <a href="/facts/Mammary_glands/6fVBnNSA">mammary glands</a> of <a href="/facts/Oestrogen/dPEewnDV">oestrogen</a> and <a href="/facts/Progesterone/WEj2TGRm">progesterone</a>-treated rats. Pinc may be a <a href="/facts/Mammal/phSwTzBo">mammal</a>-specific gene. It is conserved in a number of mammalian <a href="/facts/Genomes/tjhWET4V">genomes</a> (<a href="/facts/Human/rlcTENsr">human</a>, <a href="/facts/Mouse/6m1X7m0g">mouse</a>, <a href="/facts/Rat/5rn6uEKM">rat</a>, <a href="/facts/Common_chimpanzee/JXSpFsHy">chimpanzee</a>, <a href="/facts/Dog/DvQVRVzy">dog</a>, <a href="/facts/Cow/44qV9B6S">cow</a> and <a href="/facts/Opossum/UEhq5mkq">opossum</a>), but not in <a href="/facts/Fugu/YohoqCF8">fugu</a>, <a href="/facts/Zebrafish/Nxg1F1mG">zebrafish</a> or <a href="/facts/Xenopus/AfAtcsyA">xenopus</a> genomes.
</p><p>In mice, Pinc is expressed in the developing <a href="/facts/Embryo/9QHnLVLN">embryo</a> and in the mammary glands of adults. Its expression in the mammary gland is <a href="/facts/Regulation_of_gene_expression/9N4G341I">induced</a> by pregnancy and drops during <a href="/facts/Lactation/0w1HoW27">lactation</a>. It may have a role in <a href="/facts/Cell_(biology)/bLM9UQvy">cell</a> survival and in the regulation of <a href="/facts/Cell_cycle/nLMT7K4r">cell cycle</a> progression.
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Pinc open-in-new

Pinc