Golgi's method

Golgi's method is a <a href="/facts/Silver_staining/utsAYFFF">silver staining</a> technique that is used to visualize <a href="/facts/Nervous_tissue/YY7qG0WD">nervous tissue</a> under light microscopy. The method was discovered by <a href="/facts/Camillo_Golgi/Yq3cs6JY">Camillo Golgi</a>, an <a href="/facts/Italy/tUf0PDYF">Italian</a> <a href="/facts/Physician/qJ3woFvG">physician</a> and <a href="/facts/Scientist/JDvthEFM">scientist</a>, who published the first picture made with the technique in 1873. It was initially named the black reaction (la reazione nera) by Golgi, but it became better known as the Golgi stain or later, Golgi method.
Golgi staining was used by <a href="/facts/Spain/bIyrB8EY">Spanish</a> <a href="/facts/Neuroanatomist/VJxVXoWm">neuroanatomist</a> <a href="/facts/Santiago_Ram%25C3%25B3n_y_Cajal/EUCn9yFv">Santiago Ramón y Cajal</a> (1852–1934) to discover a number of novel facts about the organization of the nervous system, inspiring the birth of the <a href="/facts/Neuron_doctrine/kXGAzI0o">neuron doctrine</a>. Ultimately, Ramón y Cajal improved the technique by using a method he termed "double impregnation". Ramón y Cajal's staining technique, still in use, is called Cajal's stain.

Golgi's method open-in-new

Golgi's method