Targeted alpha-particle therapy

<p>Targeted alpha-particle therapy (or TAT) is an in-development method of targeted <a href="/facts/Radionuclide/5WpCfbdq">radionuclide</a> therapy of various <a href="/facts/Cancer/PVW6n1D0">cancers</a>. It employs <a href="/facts/Radioactive/Ya6FVjt4">radioactive</a> substances which undergo <a href="/facts/Alpha_decay/rCsHNIUE">alpha decay</a> to treat diseased tissue at close proximity. It has the potential to provide highly targeted treatment, especially to <a href="/facts/Microscopic/EHg18xvy">microscopic</a> <a href="/facts/Tumour/K0ytzmPz">tumour</a> <a href="/facts/Cell_(biology)/bLM9UQvy">cells</a>. Targets include <a href="/facts/Leukemia/WpEfW0Qh">leukemias</a>, <a href="/facts/Lymphoma/418wcMEl">lymphomas</a>, <a href="/facts/Glioma/I2gN3x11">gliomas</a>, <a href="/facts/Melanoma/qdT7E97Y">melanoma</a>, and <a href="/facts/Primary_peritoneal_carcinoma/G31xEa0y">peritoneal carcinomatosis</a>. As in diagnostic <a href="/facts/Nuclear_medicine/L9Dzjd90">nuclear medicine</a>, appropriate radionuclides can be <a href="/facts/Chemical_bond/ArNUMnIB">chemically bound</a> to a targeting <a href="/facts/Biomolecule/DGvFzN7R">biomolecule</a> which carries the combined <a href="/facts/Radiopharmaceutical/x3g6zbB6">radiopharmaceutical</a> to a specific treatment point.
</p><p>It has been said that "α-emitters are indispensable with regard to optimisation of strategies for tumour therapy".
</p>

Targeted alpha-particle therapy open-in-new

Targeted alpha-particle therapy