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Ion interaction chromatography
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<p>Ion interaction chromatography (ion-pair chromatography) is a <a href="/facts/Laboratory_technique/kqR3Vtx9">laboratory technique</a> for separating <a href="/facts/Ion/3bePpDna">ions</a> with <a href="/facts/Chromatography/2FrvPjNV">chromatography</a>. In this technique ions are mixed with ion pairing reagents (IPR). The analyte combines with its reciprocal ion in the IPR, this corresponds to <a href="/facts/Retention_time/2FrvPjNV">retention time</a>. Often <a href="/facts/Organic_chemistry/djxhxaNg">organic</a> <a href="/facts/Salt_(chemistry)/lsSKwGpn">salts</a> are selected to pair with <a href="/facts/Solute/MGchhMQV">solute(s)</a>. The formation of this pair affects the interaction of the pair with the <a href="/facts/Chromatography/2FrvPjNV">mobile phase and the stationary phase</a>. </p>