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Solid-phase microextraction
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<p>Solid phase microextraction, or SPME, is a <a href="/facts/Solid_phase_extraction/eSlLRuak">solid phase extraction</a> sampling technique that involves the use of a fiber coated with an extracting phase, that can be a liquid (<a href="/facts/Polymer/eF32E50K">polymer</a>) or a solid (<a href="/facts/Sorbent/C56A0ASK">sorbent</a>), which extracts different kinds of <a href="/facts/Analyte/qWzKoY8L">analytes</a> (including both <a href="/facts/Volatility_(chemistry)/90r3ep6w">volatile</a> and non-volatile) from different kinds of media, that can be in liquid or gas phase. The quantity of analyte extracted by the fibre is proportional to its concentration in the sample as long as <a href="/facts/Chemical_equilibrium/y8ToYXHp">equilibrium</a> is reached or, in case of short time pre-equilibrium, with help of <a href="/facts/Convection/E8vsCPhu">convection</a> or agitation. </p>