Jarisch–Herxheimer reaction

<p>A Jarisch–Herxheimer reaction is a sudden and typically transient reaction that may occur within 24 hours of being administered <a href="/facts/Antibiotics/sF1kIfxg">antibiotics</a> for an infection by a <a href="/facts/Spirochete/UAy2oy6I">spirochete</a>, including <a href="/facts/Syphilis/fdnGLyLT">syphilis</a>, <a href="/facts/Leptospirosis/4MSPDpnY">leptospirosis</a>, <a href="/facts/Lyme_disease/820IycaC">Lyme disease</a>, and <a href="/facts/Relapsing_fever/NCbpFTm6">relapsing fever</a>. Signs and symptoms include <a href="/facts/Fever/waVxR2Ac">fever</a>, <a href="/facts/Chills/lqjTeJ1H">chills</a>, <a href="/facts/Rigor/v23FKfhw">shivers</a>, feeling sick, headache, <a href="/facts/Tachycardia/ycmyzP7q">fast heart beat</a>, <a href="/facts/Hypotension/BhrdVVRS">low blood pressure</a>, <a href="/facts/Hyperventilation/ElocGGlI">breathing fast</a>, flushing of skin, <a href="/facts/Myalgia/AbVybHB8">muscle aches</a>, and worsening of skin lesions. It may sometimes be mistaken as an allergy to the antibiotic.
</p><p>Jarisch–Herxheimer reactions can be life-threatening because they can cause a significant drop in blood pressure and cause acute end-organ injury, eventually leading to multi-organ failure.
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Jarisch–Herxheimer reaction open-in-new

Jarisch–Herxheimer reaction