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Reference.org
KCNK2
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<p>Potassium channel subfamily K member 2, also known as TREK-1, is a <a href="/facts/Protein/Jxmagu3E">protein</a> that in humans is encoded by the <i>KCNK2</i> <a href="/facts/Gene/e1swwPY6">gene</a>. </p><p>This gene encodes K2P2.1, a <a href="/facts/Lipid-gated_ion_channels/GAU2oUJK">lipid-gated ion channel</a> belonging to the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that releases potassium out of the cell to control resting membrane potential. The channel is opened by anionic lipid, certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. </p>