DMSO reductase

<p>DMSO reductase is a <a href="/facts/Molybdenum/RX6vp2bF">molybdenum</a>-containing enzyme that catalyzes reduction of <a href="/facts/Dimethyl_sulfoxide/T4HSYfuC">dimethyl sulfoxide</a> (DMSO) to <a href="/facts/Dimethyl_sulfide/mUrg1jol">dimethyl sulfide</a> (DMS).  This enzyme serves as the terminal <a href="/facts/Oxidoreductase/neW0G5D4">reductase</a> under anaerobic conditions in some bacteria, with DMSO being the terminal electron acceptor. During the course of the reaction, the oxygen atom in DMSO is transferred to molybdenum, and then reduced to water.
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<p>DMSO reductase (DMSOR) and other members of the DMSO reductase family are unique to bacteria and <a href="/facts/Archaea/Adxh0aHw">archaea</a>. Enzymes of this family in anaerobic <a href="/facts/Oxidative_phosphorylation/en2l08P9">oxidative phosphorylation</a> and inorganic-donor-based <a href="/facts/Lithotroph/1CboHMzX">lithotrophic</a> respiration.  These enzymes have been engineered to degrade oxoanions.
DMSOR catalyzes the transfer of two electrons and one oxygen atom in the reaction: The active site of DMSOR contains molybdenum, which is otherwise rare in biology.
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DMSO reductase open-in-new

DMSO reductase