There are 20 isotopes of sodium (11Na), ranging from 17Na to 39Na (except for the still-unknown 36Na and 38Na), and five isomers (two for 22Na, and one each for 24Na, 26Na, and 32Na). 23Na is the only stable (and the only primordial) isotope. It is considered a monoisotopic element and it has a standard atomic weight of 22.98976928(2). Sodium has two radioactive cosmogenic isotopes (22Na, with a half-life of 2.6019(6) years; and 24Na, with a half-life of 14.9560(15) h). With the exception of those two isotopes, all other isotopes have half-lives under a minute, most under a second. The shortest-lived is the unbound 18Na, with a half-life of 1.3(4)×10−21 seconds (although the half-life of the similarly unbound 17Na is not measured).
Acute neutron radiation exposure (e.g., from a nuclear criticality accident) converts some of the stable 23Na (in the form of Na+ ion) in human blood plasma to 24Na. By measuring the concentration of this isotope, the neutron radiation dosage to the victim can be computed.
22Na is a positron-emitting isotope with a remarkably long half-life. It is used to create test-objects and point-sources for positron emission tomography.