Haloform reaction

<p>In <a href="/facts/Chemistry/SrNqkGVm">chemistry</a>, the haloform reaction (also referred to as the Lieben haloform reaction) is a <a href="/facts/Chemical_reaction/GpqWlKrz">chemical reaction</a> in which a <a href="/facts/Haloform/BEs2c6w2">haloform</a> (CHX3, where X is a <a href="/facts/Halogen/YeFgWHeA">halogen</a>) is produced by the exhaustive <a href="/facts/Halogenation/vYrGVWcJ">halogenation</a> of an <a href="/facts/Acetyl_group/rRmtXdn3">acetyl group</a> (R−C(=O)CH3, where R can be either a hydrogen atom, an <a href="/facts/Alkyl/vmEk8X4v">alkyl</a> or an <a href="/facts/Aryl_group/M3z7QRXd">aryl group</a>), in the presence of a <a href="/facts/Base_(chemistry)/M9wA7qeM">base</a>. The reaction can be used to transform acetyl groups into <a href="/facts/Carboxyl_group/U4xuMosy">carboxyl groups</a> (R−C(=O)OH) or to produce <a href="/facts/Chloroform/gvzuJMXa">chloroform</a> (CHCl3), <a href="/facts/Bromoform/jhmbBrtg">bromoform</a> (CHBr3), or <a href="/facts/Iodoform/4px54h0s">iodoform</a> (CHI3). Note that <a href="/facts/Fluoroform/vtMbDNbb">fluoroform</a> (CHF3) can't be prepared in this way.
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Haloform reaction open-in-new

Haloform reaction