Recombinant antibodies

<p>Recombinant antibodies are <a href="/facts/Antibody/MX8pdTdP">antibody</a> fragments produced by using recombinant antibody <a href="/facts/Gene/e1swwPY6">coding genes</a>. They mostly consist of a <a href="/facts/Heavy-chain_antibody/0nznqVA2">heavy</a> and <a href="/facts/Polypeptide/C4ltc7UG">light chain</a> of the <a href="/facts/Variable_region/MX8pdTdP">variable region</a> of <a href="/facts/Immunoglobulin/MX8pdTdP">immunoglobulin</a>. Recombinant antibodies have many advantages in both medical and research applications, which make them a popular subject of exploration and new production against specific targets. The most commonly used form is the <a href="/facts/Single_chain_variable_fragment/pyPjoIVn">single chain variable fragment</a> (scFv), which has shown the most promising traits exploitable in human medicine and research. In contrast to <a href="/facts/Monoclonal_antibody/4rUBWB87">monoclonal antibodies</a> produced by <a href="/facts/Hybridoma_technology/TstnnheP">hybridoma technology</a>, which may lose the capacity to produce the desired antibody over time, or the antibody may undergo unwanted changes that affect its functionality, recombinant antibodies produced in <a href="/facts/Phage_display/m9UYjyC4">phage display</a> maintain a high standard of <a href="/facts/Specificity_(biochemistry)/zAzbLh09">specificity</a> and low <a href="/facts/Immunogenicity/QVxzK4tD">immunogenicity</a>.
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Recombinant antibodies open-in-new

Recombinant antibodies