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In vivo bioreactor
open-in-new
<p>The <i>in vivo</i> bioreactor is a <a href="/facts/Tissue_engineering/Tx77KG1S">tissue engineering</a> paradigm that uses <a href="/facts/Bioreactor/hkUGIbCy">bioreactor</a> methodology to grow neotissue <i>in vivo</i> that augments or replaces malfunctioning native tissue. Tissue engineering principles are used to construct a confined, artificial bioreactor space <i><a href="/facts/In_vivo/kWcWyl6f">in vivo</a></i> that hosts a <a href="/facts/Tissue_scaffold/Tx77KG1S">tissue scaffold</a> and key biomolecules necessary for neotissue growth. Said space often requires inoculation with pluripotent or specific <a href="/facts/Stem_cell/qgB9dFrI">stem cells</a> to encourage initial growth, and access to a blood source. A blood source allows for recruitment of stem cells from the body alongside nutrient delivery for continual growth. This delivery of cells and nutrients to the <a href="/facts/Bioreactor/hkUGIbCy">bioreactor</a> eventually results in the formation of a neotissue product. </p>