Transmetalation

<p>Transmetalation (alt. spelling: transmetallation) is a type of <a href="/facts/Organometallic_chemistry/bhqFz2P0">organometallic</a> reaction that involves the transfer of <a href="/facts/Ligand/6etB3qeW">ligands</a> from one metal to another. It has the general form:
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M1–R + M2–R′ → M1–R′ + M2–R
<p>where R and R′ can be, but are not limited to, an <a href="/facts/Alkyl/vmEk8X4v">alkyl</a>, <a href="/facts/Aryl/M3z7QRXd">aryl</a>, <a href="/facts/Alkynyl/VHI4N5Wo">alkynyl</a>, <a href="/facts/Allyl/CDxPwyvF">allyl</a>, <a href="/facts/Halogen/YeFgWHeA">halogen</a>, or <a href="/facts/Pseudohalogen/9DMN43ya">pseudohalogen</a> group. The reaction is usually an <a href="/facts/Irreversible_process/k7PH6Muk">irreversible process</a> due to <a href="/facts/Thermodynamics/q4hIx3yP">thermodynamic</a> and kinetic reasons. Thermodynamics will favor the reaction based on the <a href="/facts/Electronegativity/H7Vq7Uah">electronegativities</a> of the metals and <a href="/facts/Kinetics_(chemistry)/D8vyX4aE">kinetics</a> will favor the reaction if there are empty orbitals on both metals. There are different types of transmetalation including redox-transmetalation and redox-transmetalation/ligand exchange. During transmetalation the metal-carbon bond is activated, leading to the formation of new metal-carbon bonds. Transmetalation is commonly used in <a href="/facts/Catalysis/LPBS7TQC">catalysis</a>, synthesis of <a href="/facts/Main_group_element/2AG3QxJl">main group</a> complexes, and synthesis of <a href="/facts/Transition_metal/0slGWoLQ">transition metal</a> complexes.
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Transmetalation open-in-new

Transmetalation