Heck reaction

<p>The Heck reaction (also called the Mizoroki–Heck reaction) is the <a href="/facts/Chemical_reaction/GpqWlKrz">chemical reaction</a> of an unsaturated <a href="/facts/Halide/ujYu8kGD">halide</a> (or <a href="/facts/Triflate/6sbvDSyt">triflate</a>) with an <a href="/facts/Alkene/RtYcS6kU">alkene</a> in the presence of a <a href="/facts/Base_(chemistry)/M9wA7qeM">base</a> and a <a href="/facts/Palladium_catalyst/P7y0ESWf">palladium catalyst</a>  to form a substituted alkene. It is named after Tsutomu Mizoroki and <a href="/facts/Richard_F._Heck/IJsACfCd">Richard F. Heck</a>. Heck was awarded the 2010 <a href="/facts/Nobel_Prize_in_Chemistry/8Nb8Ajjy">Nobel Prize in Chemistry</a>, which he shared with <a href="/facts/Ei-ichi_Negishi/jkDVKS99">Ei-ichi Negishi</a> and <a href="/facts/Akira_Suzuki_(chemist)/T2s3QYRx">Akira Suzuki</a>, for the discovery and development of this reaction. This reaction was the first example of a carbon-carbon bond-forming reaction that followed a Pd(0)/Pd(II) catalytic cycle, the same catalytic cycle that is seen in other Pd(0)-catalyzed <a href="/facts/Cross-coupling_reaction/cF8RBvCx">cross-coupling reactions</a>. The Heck reaction is a way to substitute alkenes.
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<table><tbody><tr><td></td></tr><tr><th>The Heck reaction</th></tr></tbody></table>

Heck reaction open-in-new

Heck reaction