Iran and Israel have had no diplomatic relations since 1979, and modern relations are hostile. The relationship was cordial for most of the Cold War, but worsened following the Iranian Revolution and has been openly hostile since the end of the Gulf War in 1991. Iran's current government does not recognize Israel's legitimacy as a state and has called for its destruction; it views Palestine as the sole legitimate government of the historic Palestinian territories. Israel considers Iran a threat to the Middle East's stability and has targeted Iranian assets in assassinations and airstrikes. In 2025, the hostility escalated to an armed conflict.
In 1947, Iran was among 13 countries that voted against the United Nations Partition Plan for the British Mandate of Palestine. Two years later, Iran also voted against Israel's admission to the United Nations. However, Iran was the second Muslim-majority country to recognize Israel as a sovereign state after Turkey. After the 1953 coup d'état, which reinstalled the pro-Western leader Mohammad Reza Pahlavi as the shah of Iran, relations between the two countries significantly improved. After the Iranian revolution—in which Pahlavi was ousted and Iran's secular monarchy was replaced by an anti-Western Islamic republic—Iran severed diplomatic and commercial ties with Israel, although relations continued covertly during the Iran–Iraq War (1980–1988).
Since 1985, Iran and Israel have been engaged in a proxy conflict that has greatly affected the geopolitics of the Middle East. The turn from cold peace to open hostility began in the early 1990s, shortly after the collapse of the Soviet Union and the defeat of Iraq in the Gulf War. Israeli prime minister Yitzhak Rabin's government adopted a more aggressive posture on Iran, and Iranian president Mahmoud Ahmadinejad made inflammatory statements against Israel. Other factors contributing to the escalation of tensions include the Iranian nuclear program, Iran's funding of Islamist groups such as Hezbollah, Palestinian Islamic Jihad, Hamas, and the Houthis, and Iran's involvement in attacks such as the 1992 Buenos Aires Israeli embassy bombing and the 1994 AMIA bombing, as well as Israeli threats of military action.
Iranian and Israeli organizations have been involved in direct military confrontations, such as in the 2006 Lebanon War. Iran and Israel have provided support for opposing factions in the Syrian and Yemeni civil wars and conducted cyberattacks and sabotage against each other's infrastructure, including attacks on nuclear facilities and oil tankers. Iran's proxy conflict with Saudi Arabia has led to an informal alliance between Israel and Arab states. In 2024, amid increasing regional tensions stemming from the Gaza war, Iran–Israel tensions escalated to a period of direct conflict; both carried out missile strikes on the other and Israel assassinated targets in Iran and Syria. In 2025, Israel carried out strikes against Iranian nuclear and military targets a day after the International Atomic Energy Agency declared that Iran had violated its obligations regarding nuclear proliferation, sparking a war between the countries.