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Codeine-6-glucuronide
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<p>Codeine-6-glucuronide (C6G) is a major active metabolite of <a href="/facts/Codeine/lr7WHXmX">codeine</a> and may be responsible for as much as 60% of the <a href="/facts/Analgesic/xLj4XBcq">analgesic</a> effects of codeine. C6G exhibits decreased immunosuppressive effects compared to codeine. During its metabolism, codeine is conjugated with <a href="/facts/Glucuronic_acid/hPverAR8">glucuronic acid</a> by the enzyme <a href="/facts/UGT2B7/GbcdPo5f">UDP-Glucuronosyltransferase-2B7</a> (UGT2B7) to form codeine-6-glucuronide. </p>