During his college days, Murugadoss was active in cultural events, particularly in mimicry and drawing. He subsequently became a cinephile watching up to seven films a week in his hometown and started writing jokes as well. After Ananda Vikatan published them, Murugadoss began to think of becoming a story writer. At Bharathidasan University he started to write sketch comedies and acted in them. After college he tried to join the Madras Film Institute, but was rejected. Nevertheless, Murugadoss stayed in Chennai in multiple functions. First, he became an assistant writer of P. Kalaimani and wrote dialogues for the Tamil film Madurai Meenakshi. He became assistant director of Ratchagan (1997) for half of the film and continued as assistant script director for the Telugu film Kalusukundam Ra. Murugadoss then worked with S. J. Surya for the film Kushi.
After a gap of 5 years, Murugadoss made his directorial comeback in 2025 with two highly anticipated films - Sikandar with Salman Khan which released on Eid-ul-Fitr, and Madharasi with Sivakarthikeyan.
This is a list of films in which AR Murugadoss worked for other directors.
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