Menu
Home
People
Places
Arts
History
Plants & Animals
Science
Life & Culture
Technology
Reference.org
Pherine
open-in-new
<h2 id="examples-of-pherines">Examples of pherines</h2> <ul><li><a href="/facts/Fasedienol/mF57uNwY">Fasedienol</a> (PH94B; Aloradine; 4,16-androstadien-3β-ol) is an investigational new drug proposed for the acute treatment of <a href="/facts/Social_anxiety_disorder/25XIzJ0o">social anxiety disorder</a>.<a class="footnote-ref" id="fnref:20" href="#fn:20"><sup>20</sup></a><a class="footnote-ref" id="fnref:21" href="#fn:21"><sup>21</sup></a></li> <li><a href="/facts/PH10_(drug)/pqlfy0yG">PH10</a> is being developed as an indication for the acute treatment of <a href="/facts/Depression_(mood)/GDNFWm1L">depression</a>.<a class="footnote-ref" id="fnref:22" href="#fn:22"><sup>22</sup></a></li> <li>PH80. In clinical trials this pherine molecule showed efficacy to relieve premenstrual symptoms and it is also being studied for its beneficial effect to reduce menopausal hot flashes.<a class="footnote-ref" id="fnref:23" href="#fn:23"><sup>23</sup></a></li> <li>PH15 is in early stage development for the treatment of <a href="/facts/Cognitive_impairment/VhJVfJ8a">cognitive impairment</a>.</li></ul> <h2 id="see-also">See also</h2> <ul><li><a href="/facts/List_of_neurosteroids/6dWIMHhF">List of neurosteroids</a></li></ul> <h2 id="references">References</h2> <ol> <li id="fn:1"><p>Liebowitz, Michael R.; Salman, Ester; Nicolini, Humberto; Rosenthal, Norman; Hanover, Rita; Monti, Louis (2014). "Effect of an Acute Intranasal Aerosol Dose of PH94B on Social and Performance Anxiety in Women With Social Anxiety Disorder". American Journal of Psychiatry. 171 (6): 675–682. doi:10.1176/appi.ajp.2014.12101342. ISSN 0002-953X. PMID 24700254. S2CID 38510058. <a href="https://www.researchgate.net/publication/261511611" target="_blank">https://www.researchgate.net/publication/261511611</a> <a href="#fnref:1" class="footnote-back-ref">↩</a></p></li> <li id="fn:2"><p>Monti-Bloch, L.; Jennings-White, C.; Dolberg, D.S.; Berliner, D.L. (1994). "The human vomeronasal system". Psychoneuroendocrinology. 19 (5–7): 673–686. doi:10.1016/0306-4530(94)90049-3. ISSN 0306-4530. PMID 7938363. S2CID 36129626. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:2" class="footnote-back-ref">↩</a></p></li> <li id="fn:3"><p>Berliner DL, Monti-Bloch L, Jennings-White C, Diaz-Sanchez V (1996). "The functionality of the human vomeronasal organ (VNO): evidence for steroid receptors". J. Steroid Biochem. Mol. Biol. 58 (3): 259–65. doi:10.1016/0960-0760(96)00062-3. PMID 8836161. S2CID 31206207. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:3" class="footnote-back-ref">↩</a></p></li> <li id="fn:4"><p>Monti-Bloch L, Diaz-Sanchez V, Jennings-White C, Berliner DL (1998). "Modulation of serum testosterone and autonomic function through stimulation of the male human vomeronasal organ (VNO) with pregna-4,20-diene-3,6-dione". J. Steroid Biochem. Mol. Biol. 65 (1–6): 237–42. doi:10.1016/s0960-0760(98)00025-9. PMID 9699878. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:4" class="footnote-back-ref">↩</a></p></li> <li id="fn:5"><p>Liebowitz, Michael R.; Salman, Ester; Nicolini, Humberto; Rosenthal, Norman; Hanover, Rita; Monti, Louis (2014). "Effect of an Acute Intranasal Aerosol Dose of PH94B on Social and Performance Anxiety in Women With Social Anxiety Disorder". American Journal of Psychiatry. 171 (6): 675–682. doi:10.1176/appi.ajp.2014.12101342. ISSN 0002-953X. PMID 24700254. S2CID 38510058. <a href="https://www.researchgate.net/publication/261511611" target="_blank">https://www.researchgate.net/publication/261511611</a> <a href="#fnref:5" class="footnote-back-ref">↩</a></p></li> <li id="fn:6"><p>Monti-Bloch, L.; Jennings-White, C.; Dolberg, D.S.; Berliner, D.L. (1994). "The human vomeronasal system". Psychoneuroendocrinology. 19 (5–7): 673–686. doi:10.1016/0306-4530(94)90049-3. ISSN 0306-4530. PMID 7938363. S2CID 36129626. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:6" class="footnote-back-ref">↩</a></p></li> <li id="fn:7"><p>Berliner DL, Monti-Bloch L, Jennings-White C, Diaz-Sanchez V (1996). "The functionality of the human vomeronasal organ (VNO): evidence for steroid receptors". J. Steroid Biochem. Mol. Biol. 58 (3): 259–65. doi:10.1016/0960-0760(96)00062-3. PMID 8836161. S2CID 31206207. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:7" class="footnote-back-ref">↩</a></p></li> <li id="fn:8"><p>Monti-Bloch L, Diaz-Sanchez V, Jennings-White C, Berliner DL (1998). "Modulation of serum testosterone and autonomic function through stimulation of the male human vomeronasal organ (VNO) with pregna-4,20-diene-3,6-dione". J. Steroid Biochem. Mol. Biol. 65 (1–6): 237–42. doi:10.1016/s0960-0760(98)00025-9. PMID 9699878. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:8" class="footnote-back-ref">↩</a></p></li> <li id="fn:9"><p>Monti-Bloch, L; Jennings-White, C; Berliner, DL (1988). "The human vomeronasal system: a review". Ann NY Acad Sci. 855: 373–89. doi:10.1111/j.1749-6632.1998.tb10595.x. PMID 9929629. S2CID 38973467. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:9" class="footnote-back-ref">↩</a></p></li> <li id="fn:10"><p>Winegar, B; Monti-Bloch, L (2003). "Vomeropherins produce low-frequency calcium oscillations in human vomeronasal neurons". Chem Senses. 25th ACHEMS Meeting (Sarasota, FL): 83. <a href="#fnref:10" class="footnote-back-ref">↩</a></p></li> <li id="fn:11"><p>Sobel, N; Prabhakaran, V; Hartley, CA; Desmond, JE; Glover, GH; Sullivan, EV; Gabrieli, JD (1999). "Blind smell: brain activation induced by an undetected air-borne chemical". Brain. 122 (Pt 2): 209–17. doi:10.1093/brain/122.2.209. PMID 10071050. <a href="/wiki/Catherine_Hartley" target="_blank">/wiki/Catherine_Hartley</a> <a href="#fnref:11" class="footnote-back-ref">↩</a></p></li> <li id="fn:12"><p>Freeman, E; Monti-Bloch, L (2007). "Evaluation of a unique new intranasal aerosol in the treatment of clinically significant premenstrual syndrome". 47th NCDEU Meeting (Boca Raton, Florida). {{cite journal}}: Cite journal requires |journal= (help) <a href="/wiki/Template:Cite_journal" target="_blank">/wiki/Template:Cite_journal</a> <a href="#fnref:12" class="footnote-back-ref">↩</a></p></li> <li id="fn:13"><p>Liebowitz, MR; Salman, E; Nicolini, H; Rosenthal, N; Hanover, R; Monti, L (2014). "Effect of an acute intranasal aerosol dose of PH94B on social and performance anxiety in women with social anxiety disorder". Am J Psychiatry. 171 (6): 675–82. doi:10.1176/appi.ajp.2014.12101342. PMID 24700254. S2CID 38510058. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:13" class="footnote-back-ref">↩</a></p></li> <li id="fn:14"><p>Liebowitz, MR; Nicolini, H; Monti, L; Hanover, R (2013). "PH 10 may be a new rapidly acting intranasally administered antidepressant". American Society of Clinical Psychopharmacology (ASCP) Annual Meeting, Miami, Florida. {{cite journal}}: Cite journal requires |journal= (help) <a href="/wiki/Template:Cite_journal" target="_blank">/wiki/Template:Cite_journal</a> <a href="#fnref:14" class="footnote-back-ref">↩</a></p></li> <li id="fn:15"><p>Liebowitz, Michael R.; Salman, Ester; Nicolini, Humberto; Rosenthal, Norman; Hanover, Rita; Monti, Louis (2014). "Effect of an Acute Intranasal Aerosol Dose of PH94B on Social and Performance Anxiety in Women With Social Anxiety Disorder". American Journal of Psychiatry. 171 (6): 675–682. doi:10.1176/appi.ajp.2014.12101342. ISSN 0002-953X. PMID 24700254. S2CID 38510058. <a href="https://www.researchgate.net/publication/261511611" target="_blank">https://www.researchgate.net/publication/261511611</a> <a href="#fnref:15" class="footnote-back-ref">↩</a></p></li> <li id="fn:16"><p>Monti-Bloch, L.; Jennings-White, C.; Dolberg, D.S.; Berliner, D.L. (1994). "The human vomeronasal system". Psychoneuroendocrinology. 19 (5–7): 673–686. doi:10.1016/0306-4530(94)90049-3. ISSN 0306-4530. PMID 7938363. S2CID 36129626. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:16" class="footnote-back-ref">↩</a></p></li> <li id="fn:17"><p>Berliner DL, Monti-Bloch L, Jennings-White C, Diaz-Sanchez V (1996). "The functionality of the human vomeronasal organ (VNO): evidence for steroid receptors". J. Steroid Biochem. Mol. Biol. 58 (3): 259–65. doi:10.1016/0960-0760(96)00062-3. PMID 8836161. S2CID 31206207. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:17" class="footnote-back-ref">↩</a></p></li> <li id="fn:18"><p>Monti-Bloch L, Diaz-Sanchez V, Jennings-White C, Berliner DL (1998). "Modulation of serum testosterone and autonomic function through stimulation of the male human vomeronasal organ (VNO) with pregna-4,20-diene-3,6-dione". J. Steroid Biochem. Mol. Biol. 65 (1–6): 237–42. doi:10.1016/s0960-0760(98)00025-9. PMID 9699878. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:18" class="footnote-back-ref">↩</a></p></li> <li id="fn:19"><p>Monti-Bloch, Louis; Jennings-White, Clive; Berliner, David L. (1998). "The Human Vomeronasal System: A Review". Annals of the New York Academy of Sciences. 855 (1 OLFACTION AND): 373–389. Bibcode:1998NYASA.855..373M. doi:10.1111/j.1749-6632.1998.tb10595.x. ISSN 0077-8923. PMID 9929629. S2CID 38973467. <a href="/wiki/Bibcode_(identifier)" target="_blank">/wiki/Bibcode_(identifier)</a> <a href="#fnref:19" class="footnote-back-ref">↩</a></p></li> <li id="fn:20"><p>Liebowitz, MR; Salman, E; Nicolini, H; Rosenthal, N; Hanover, R; Monti, L (2014). "Effect of an acute intranasal aerosol dose of PH94B on social and performance anxiety in women with social anxiety disorder". Am J Psychiatry. 171 (6): 675–82. doi:10.1176/appi.ajp.2014.12101342. PMID 24700254. S2CID 38510058. <a href="/wiki/Doi_(identifier)" target="_blank">/wiki/Doi_(identifier)</a> <a href="#fnref:20" class="footnote-back-ref">↩</a></p></li> <li id="fn:21"><p>Liebowitz, M; Monti, L; Hanover, R; Draine, A (2015). "PH94B nasal spray as a PRN treatment for social anxiety disorder: a phase 3 pilot trial". ASCP Annual Meeting: T13. {{cite journal}}: Cite journal requires |journal= (help) <a href="/wiki/Template:Cite_journal" target="_blank">/wiki/Template:Cite_journal</a> <a href="#fnref:21" class="footnote-back-ref">↩</a></p></li> <li id="fn:22"><p>Liebowitz, MR; Nicolini, H; Monti, L; Hanover, R (2013). "PH 10 may be a new rapidly acting intranasally administered antidepressant". American Society of Clinical Psychopharmacology (ASCP) Annual Meeting, Miami, Florida. {{cite journal}}: Cite journal requires |journal= (help) <a href="/wiki/Template:Cite_journal" target="_blank">/wiki/Template:Cite_journal</a> <a href="#fnref:22" class="footnote-back-ref">↩</a></p></li> <li id="fn:23"><p>Freeman, E; Monti-Bloch, L (2007). "Evaluation of a unique new intranasal aerosol in the treatment of clinically significant premenstrual syndrome". 47th NCDEU Meeting (Boca Raton, Florida). {{cite journal}}: Cite journal requires |journal= (help) <a href="/wiki/Template:Cite_journal" target="_blank">/wiki/Template:Cite_journal</a> <a href="#fnref:23" class="footnote-back-ref">↩</a></p></li> </ol>